rockhillmanor
On the Road
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Joined: 12/06/2003
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I disagree.
Not to mention my old standby answer. Most animal feed testing and med dosage testing is done on mid sized dogs. I get the reason they do it.
Which does not reflect exactly what the results would be in a Giant Breed or more importantly small breeds, not to mention the sensitivity of certain breeds.
The tests by nature have a plus minus variable to begin with. Not to mention the lack of testing of ppms at the raw ingredient stage and upon arrival at food manuf plants. And you have to include the docs of letters from industries to FDA that state they can 'not' maintain that particular level and FDA changes the level to accommodate big business after the first reports come out publicly.
Sorry if something is known to cause cancer at "ANY LEVEL", it should not be allowed, but because of big business it sadly is allowed into the food chain.
The best example of this is when BSE reared its ugly head. FDA jumped on it and set standards to keep us safe and there where immediately letters from the "Cattle Industry" saying they could not comply and still make money.....the FDA changed the standards.
If an ingredient is known to cause cancer in a specific organ at X amount. Can anyone honestly think that eating an amount of a 'known cancer causing' ingredient just less than X amount long term is not going to cause cancer? 
We must be willing to get rid of the life we've planned,
so as to have the life that is waiting for us.
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BCSnob
Middletown, MD
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Joined: 02/23/2002
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rockhillmanor wrote:If an ingredient is known to cause cancer in a specific organ at X amount. Can anyone honestly think that eating an amount of a 'known cancer causing' ingredient just less than X amount long term is not going to cause cancer? Are you not listening to the drug ads on TV?  There are many things we consume that above certain levels are toxic and/or carcinogenic but we continue to consume them at lower levels (below which they have been shown to have no adverse effects within the limits of the testing performed).
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A recent example of us consuming large quantities of a known carcinogen
4-methylimidazole aka Caramel Color
If this proves true for all levels of 4-methylimidazole you must give up colas, beers, coffee, soy sauce, etc.
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The animal feed testing experiments use the amounts of an ingredient in the final form of the feed. This is very obvious in the "experimnetal" sections of the feed studies.
There is no need to tell me about uncertainties and confidence intervals in median or mean test results; I work with these every day.
Ethoxyquin does a better job at preventing the oxidation of fats than other anti-oxidants (including vitamin C and tocopherols); ethoxyquin survives through the manufacturing process while the others must be sprayed on after extrusion. You should know that the oxidation products of fats are carcinogenic.
I agree that there is insufficient safety testing performed on various sub-populations (children, women, age and size groups, etc). Are you willing to pay a lot more for everything in order to cover the costs of the expanded test groups and extended test times?
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BCSnob
Middletown, MD
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Joined: 02/23/2002
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rockhillmanor wrote:Sorry if something is known to cause cancer at "ANY LEVEL", it should not be allowed, but because of big business it sadly is allowed into the food chain.
You'd better avoid oxygen
Quote:Oxygen: our major carcinogen?
Abstract
Evidence has accumulated implicating that atmospheric oxygen can be considered as an important environmental mutagen, whose action can be potentiated by a variety of environmental factors. Under normal conditions oxygen genotoxicity is largely prevented by a cellular antioxygenic defense system, which must be extremely efficient, but might not be entirely safe. A better understanding of this defense system may help to suggest how the incidence of carcinogenesis can be minimized.
Quote:Reactive oxygen species: Role in the dev........of cancer and various chronic conditions
Abstract
Oxygen derived species such as superoxide radical, hydrogen peroxide, singlet oxygen and hydroxyl radical are well known to be cytotoxic and have been implicated in the etiology of a wide array of human diseases, including cancer. Various carcinogens may also partly exert their effect by generating reactive oxygen species (ROS) during their metabolism. Oxidative damage to cellular DNA can lead to mutations and may, therefore, play an important role in the initiation and progression of multistage carcinogenesis. The changes in DNA such as base modification, rearrangement of DNA sequence, miscoding of DNA lesion, gene duplication and the activation of oncogenes may be involved in the initiation of various cancers. Elevated levels of ROS and down regulation of ROS scavengers and antioxidant enzymes are associated with various human diseases including various cancers. ROS are also implicated in diabtes and neurodegenerative diseases. ROS influences central cellular processes such as proliferation a, apoptosis, senescence which are implicated in the development of cancer. Understanding the role of ROS as key mediators in signaling cascades may provide various opportunities for pharmacological intervention.
The following have been shown to increase the risk of some cancers when taken at higher levels (above RDA/DRI):
Betacarotene
Tocopherol
Ascorbic Acid
Folic Acid
Since Vitamin C, Tocopherols, and Ethoxyquin have all been shown to increase cancer risks when taken at higher levels than those in feeds what should feed manufacturers used as a preservative?
* This post was
edited 02/09/12 10:22am by BCSnob *
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me and my boys
CT
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Joined: 02/07/2012
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I have a family of 6-4 humans,2 goldens.I try to feed my DH and kids as few processed foods as possible but its not cheap. I would love to feed my 2 goldens the best stuff, can you suggest a good affordable dog food?
2008 Ford Expedition
2012 Skyline Joey 268
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